IgGDiaLab: Next-Generation In Vitro Diagnostics for Neuroinflammatory and Neurodegenerative Diseases

Building the laboratory foundation for early functional diagnostics

IgGDiaLab develops prototypes of key laboratory components of the dAIgnostics Apparatus: the dAI Kit for controlled in vitro testing with patient-derived IgG, and the dAI Recorder for capturing living-cell responses. Together, they form the laboratory foundation for generating functional biological data.

Funded by the European Union – NextGenerationEU. The views and opinions expressed are solely those of the author and do not necessarily reflect the official views of the European Union or the European Commission. Neither the European Union nor the European Commission can be held responsible for them.

Challenge

Conventional diagnostics often identify neurodegenerative and neuroinflammatory disease mechanisms only after structural changes or clinical symptoms become apparent. This can limit opportunities for earlier functional insight and timely intervention.

Solution

IgGDiaLab introduces a living-cell-based in vitro testing approach in which patient-derived IgG is applied to living cells under controlled laboratory conditions. The resulting physiological cell responses are recorded and prepared for downstream digital and AI-based analysis.

What IgGDiaLab develops

dAI Kit

A laboratory kit for controlled application of patient-derived IgG to living cells under standardized testing conditions.

dAI Recorder

A recording device for capturing physiological cell responses and converting them into structured data for the dAIgnostics platform.

Role within the dAIgnostics platform

IgGDiaLab supports the dAIgnostics Apparatus layer by generating reliable functional data from living-cell responses before AI-supported interpretation takes place.

Patient-derived IgG

Living-cell testing

Physiological cell response

Structured biological data

dAIgnostics platform

Related platform:

Project funding information

The project “Laboratory kit and apparatus for in vitro diagnostics based on physiological reactions of cells to patients’ immunoglobulins – IgGDiaLab” is funded by the European Union – NextGenerationEU under the National Recovery and Resilience Plan 2021–2026, Call “Proof of Innovative Concept – Third Call”, call code NPOO.C3.2.R3-I1.06.

  • Project beneficiary: DAIGNOSTICS d.o.o.
  • Project code: NPOO.C3.2.R3-I1.06.0360
  • Project acronym: IgGDiaLab
  • Project duration: 12 months from 30th of June 2025 Until 30th of June 2026

Project description

The aim of the IgGDiaLab project is to prove the innovative concept of a laboratory kit and apparatus for in vitro diagnostics based on physiological reactions of cells to patients’ immunoglobulins.

Expected project result

Expected project result: The expected result of the project is the development and demonstration of prototypes of key laboratory components, as well as the assessment of their potential for further development, intellectual property protection and commercialization.

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